Shira was born in Israel and began her piano studies at the age of four. At eight, she joined Adina Wertheim's class at the Israel Conservatory of Music, Tel Aviv, where she graduated with honors. After completing her military service as an 'Outstanding Musician', Shira enrolled at the Buchmann-Mehta School of Music at Tel Aviv University, where she earned a B.Mus degree in piano performance under the guidance of Michael Boguslavsky and Mark Shaviner. She then completed her M.Mus studies with Vadim Monastyrski at the Jerusalem Academy of Music and Dance. Mentored by Gilbert Kalish, Shira earned a Doctor of Musical Arts degree from Stony Brook University.

Since 2020, Shira has been collaborating with flutist Idit Shemer, and in 2021, Duo Lyric was born. Together, they perform a wide range of repertoire, including both old and new works, with pieces specifically dedicated to the duo. Shira participated in the Pittsburgh Jewish Music Festival, the Eilat Chamber Music Festival, the West Village Musical Theatre Festival, and the Tel Aviv Piano Festival. She has attended numerous international masterclasses with Pnina Salzman, Joanna MacGregor, Pavel Gililov, Albert Tiu, and at the Tel-Hai International Piano Master Classes.

Shira has performed at Carnegie Hall in New York, the Municipal Theatre of Santiago in Chile, the Charles Bronfman Auditorium in Tel Aviv, Jazz at Lincoln Center in New York, and the Verizon Center in Washington, D.C. She contributed significantly to two albums with Israel Prize-winning poet Nathan Zach and composer Shlomi Frige, and participated in live and studio projects with prominent artists, including guitarist-composer Yair Yona, singer- songwriter Amit Erez, and renowned violinist Maxim Vengerov, with whom she maintains an ongoing collaboration.

Shira released her debut album of solo piano recordings, RED, and has performed as a soloist with the Jerusalem Symphony Orchestra, the Stony Brook Orchestra, the Symphonette Ra’anana, and the Tel Aviv University Orchestra.